| Reserpine | The serum concentration of Acetaminophen can be decreased when it is combined with Reserpine. | Approved |
| Regorafenib | The serum concentration of Acetaminophen can be increased when it is combined with Regorafenib. | Approved |
| Reboxetine | The serum concentration of Acetaminophen can be increased when it is combined with Reboxetine. | Approved, Investigational |
| Ranolazine | The serum concentration of Ranolazine can be increased when it is combined with Acetaminophen. | Approved, Investigational |
| Ranitidine | The serum concentration of Acetaminophen can be increased when it is combined with Ranitidine. | Approved |
| Rabeprazole | The metabolism of Acetaminophen can be decreased when combined with Rabeprazole. | Approved, Investigational |
| Quinine | The serum concentration of Acetaminophen can be increased when it is combined with Quinine. | Approved |
| Quinidine | The metabolism of Acetaminophen can be decreased when combined with Quinidine. | Approved |
| Quinacrine | The serum concentration of Acetaminophen can be increased when it is combined with Quinacrine. | Approved |
| Quetiapine | The serum concentration of Quetiapine can be increased when it is combined with Acetaminophen. | Approved |
| Quercetin | The serum concentration of Acetaminophen can be increased when it is combined with Quercetin. | Experimental |
| Pyrimethamine | The metabolism of Acetaminophen can be decreased when combined with Pyrimethamine. | Approved, Vet Approved |
| Prucalopride | The serum concentration of Prucalopride can be increased when it is combined with Acetaminophen. | Approved |
| Protriptyline | The serum concentration of Acetaminophen can be increased when it is combined with Protriptyline. | Approved |
| Propranolol | The serum concentration of Propranolol can be increased when it is combined with Acetaminophen. | Approved, Investigational |
| Propafenone | The serum concentration of Acetaminophen can be increased when it is combined with Propafenone. | Approved |
| Promethazine | The serum concentration of Acetaminophen can be increased when it is combined with Promethazine. | Approved |
| Promazine | The metabolism of Acetaminophen can be decreased when combined with Promazine. | Approved, Vet Approved |
| Progesterone | The serum concentration of Acetaminophen can be decreased when it is combined with Progesterone. | Approved, Vet Approved |
| Probenecid | The serum concentration of Acetaminophen can be increased when it is combined with Probenecid. | Approved |
| Primidone | The metabolism of Acetaminophen can be increased when combined with Primidone. | Approved, Vet Approved |
| Prilocaine | The risk or severity of adverse effects can be increased when Acetaminophen is combined with Prilocaine. | Approved |
| Prednisone | The serum concentration of Prednisone can be increased when it is combined with Acetaminophen. | Approved, Vet Approved |
| Prednisolone | The serum concentration of Prednisolone can be increased when it is combined with Acetaminophen. | Approved, Vet Approved |
| Prazosin | The serum concentration of Acetaminophen can be increased when it is combined with Prazosin. | Approved |
| Pravastatin | The serum concentration of Pravastatin can be increased when it is combined with Acetaminophen. | Approved |
| Posaconazole | The metabolism of Acetaminophen can be decreased when combined with Posaconazole. | Approved, Investigational, Vet Approved |
| Ponatinib | The serum concentration of Ponatinib can be increased when it is combined with Acetaminophen. | Approved |
| Pomalidomide | The serum concentration of Pomalidomide can be increased when it is combined with Acetaminophen. | Approved |
| Platelet Activating Factor | The serum concentration of Acetaminophen can be decreased when it is combined with Platelet Activating Factor. | Experimental |
| Pitavastatin | The serum concentration of Pitavastatin can be increased when it is combined with Acetaminophen. | Approved |
| Pioglitazone | The metabolism of Acetaminophen can be decreased when combined with Pioglitazone. | Approved, Investigational |
| Pimozide | The serum concentration of Acetaminophen can be increased when it is combined with Pimozide. | Approved |
| Phenytoin | The serum concentration of Acetaminophen can be decreased when it is combined with Phenytoin. | Approved, Vet Approved |
| Phenylephrine | The serum concentration of Phenylephrine can be increased when it is combined with Acetaminophen. | Approved |
| Phenprocoumon | Acetaminophen may increase the anticoagulant activities of Phenprocoumon. | Approved |
| Phenobarbital | The metabolism of Acetaminophen can be increased when combined with Phenobarbital. | Approved |
| Phenindione | Acetaminophen may increase the anticoagulant activities of Phenindione. | Approved |
| Perindopril | The serum concentration of Acetaminophen can be increased when it is combined with Perindopril. | Approved |
| Pentobarbital | The metabolism of Acetaminophen can be increased when combined with Pentobarbital. | Approved, Vet Approved |
| Peginterferon alfa-2b | The serum concentration of Acetaminophen can be increased when it is combined with Peginterferon alfa-2b. | Approved |
| Pazopanib | The serum concentration of Pazopanib can be increased when it is combined with Acetaminophen. | Approved |
| Paroxetine | The metabolism of Acetaminophen can be decreased when combined with Paroxetine. | Approved, Investigational |
| Pantoprazole | The serum concentration of Acetaminophen can be increased when it is combined with Pantoprazole. | Approved |
| Panobinostat | The serum concentration of Acetaminophen can be increased when it is combined with Panobinostat. | Approved, Investigational |
| Palmitic Acid | The serum concentration of Acetaminophen can be increased when it is combined with Palmitic Acid. | Experimental |
| Palbociclib | The serum concentration of Acetaminophen can be increased when it is combined with Palbociclib. | Approved |
| Paclitaxel | The serum concentration of Acetaminophen can be increased when it is combined with Paclitaxel. | Approved, Vet Approved |
| P-Nitrophenol | The serum concentration of Acetaminophen can be increased when it is combined with P-Nitrophenol. | Experimental |
| Osimertinib | The serum concentration of Acetaminophen can be increased when it is combined with Osimertinib. | Approved |
| Omeprazole | The serum concentration of Acetaminophen can be increased when it is combined with Omeprazole. | Approved, Investigational, Vet Approved |
| Ombitasvir | The serum concentration of Ombitasvir can be increased when it is combined with Acetaminophen. | Approved |
| Olaparib | The metabolism of Acetaminophen can be decreased when combined with Olaparib. | Approved |
| Olanzapine | The serum concentration of Olanzapine can be increased when it is combined with Acetaminophen. | Approved, Investigational |
| Norethisterone | The serum concentration of Acetaminophen can be decreased when it is combined with Norethisterone. | Approved |
| Nizatidine | The serum concentration of Nizatidine can be increased when it is combined with Acetaminophen. | Approved |
| Nitric Oxide | The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Acetaminophen. | Approved |
| Nitrendipine | The serum concentration of Acetaminophen can be increased when it is combined with Nitrendipine. | Approved |
| Nitrazepam | The serum concentration of Acetaminophen can be increased when it is combined with Nitrazepam. | Approved |
| Nisoldipine | The serum concentration of Acetaminophen can be increased when it is combined with Nisoldipine. | Approved |
| Nintedanib | The serum concentration of Nintedanib can be increased when it is combined with Acetaminophen. | Approved |
| Nilotinib | The metabolism of Acetaminophen can be decreased when combined with Nilotinib. | Approved, Investigational |
| Nifedipine | The serum concentration of Acetaminophen can be decreased when it is combined with Nifedipine. | Approved |
| Nicotine | The metabolism of Acetaminophen can be decreased when combined with Nicotine. | Approved |
| Nicardipine | The metabolism of Acetaminophen can be decreased when combined with Nicardipine. | Approved |
| Nevirapine | The metabolism of Acetaminophen can be increased when combined with Nevirapine. | Approved |
| Netupitant | The serum concentration of Acetaminophen can be increased when it is combined with Netupitant. | Approved |
| Neostigmine | The serum concentration of Acetaminophen can be increased when it is combined with Neostigmine. | Approved, Vet Approved |
| Nelfinavir | The metabolism of Acetaminophen can be decreased when combined with Nelfinavir. | Approved |
| Nefazodone | The metabolism of Acetaminophen can be decreased when combined with Nefazodone. | Approved, Withdrawn |
| Naringenin | The serum concentration of Acetaminophen can be increased when it is combined with Naringenin. | Experimental |
| Naltrexone | The serum concentration of Acetaminophen can be increased when it is combined with Naltrexone. | Approved, Investigational, Vet Approved |
| Naloxone | The serum concentration of Naloxone can be increased when it is combined with Acetaminophen. | Approved, Vet Approved |
| Naloxegol | The serum concentration of Naloxegol can be increased when it is combined with Acetaminophen. | Approved |
| Nafcillin | The serum concentration of Acetaminophen can be decreased when it is combined with Nafcillin. | Approved |
| Nadolol | The serum concentration of Nadolol can be increased when it is combined with Acetaminophen. | Approved |
| Mycophenolate mofetil | The serum concentration of Mycophenolate mofetil can be increased when it is combined with Acetaminophen. | Approved, Investigational |
| Morphine | The serum concentration of Morphine can be increased when it is combined with Acetaminophen. | Approved, Investigational |
| Modafinil | The serum concentration of Acetaminophen can be decreased when it is combined with Modafinil. | Approved, Investigational |
| Mitoxantrone | The serum concentration of Acetaminophen can be decreased when it is combined with Mitoxantrone. | Approved, Investigational |
Ziprasidone The metabolism of Acetaminophen can be decreased when combined with Ziprasidone. Approved Zimelidine The serum concentration of Acetaminophen can be increased when it is…
Reserpine The serum concentration of Acetaminophen can be decreased when it is combined with Reserpine. Approved Regorafenib The serum concentration of Acetaminophen can be increased…
Mitotane The serum concentration of Acetaminophen can be decreased when it is combined with Mitotane. Approved Mitomycin The serum concentration of Acetaminophen can be increased…
Pain Medications, Pain Relief, and Pain Management
